深圳欣博盛生物科技有限公司 a1

anti-Netrin-1 (human), mAb (rec.) (blocking) (2F5) (preservative free) (25 ug)
货号:AG-27B-0018PF-C100 规格:100 ug 目录价:¥4320
货号:AG-27B-0018PF-C500 规格:500 ug 目录价:¥11640
货号:AG-27B-0018PF-TRIAL 规格:25 ug 目录价:¥1740
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
anti-Netrin-1 (human), mAb (rec.) (blocking) (2F5) (preservative free) (25 ug)
别名:
NTN1; NP01-014
产品描述:
Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serves as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also involved in tumorigenesis by regulating apoptosis. Netrin-1 promotes atherosclerosis by retaining macrophages in the artery wall. Netrin-1 also governs induced pluripotent stem cell (iPS) formation and improves reprogramming efficiency of human and mouse somatic cells by limiting apoptosis mediated by Netrin-1 receptors DCC or UNC5b.
宿主来源:
Produced without the use of animals. Purified from HEK 293 cell culture supernatant.
实验应用:
ELISA, FUNC (Blocking)
靶标/特异性:
Recognizes human and mouse Netrin-1. Does not recognize Netrin-4. Blocks human and mouse Netrin-1 activity on tumor cell lines in vitro and in vivo. Inhibits Netrin-1-enhanced infectivity of Hepatitis C Virus particles.
同种型:
Human IgG2lambda.
免疫原:
Recombinant human Netrin-1.
克隆号:
2F5
偶联:
Preservative Free
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
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