anti-NLRP6/NALP6 (human), mAb (Clint-1) (25 ug)-单抗-深圳欣博盛生物科技有限公司

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anti-NLRP6/NALP6 (human), mAb (Clint-1) (25 ug)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-20B-0046-C100	规格：100 ug	目录价：￥4680
货号：AG-20B-0046-TRIAL	规格：25 ug	目录价：￥1740

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-NLRP6/NALP6 (human), mAb (Clint-1) (25 ug)

别名:

NACHT-, LRR and PYD Domains-containing Protein 6; Nod-like Receptor Pyrin Domain-containing Protein 6; NLRP6; Angiotensin II/Vasopressin Receptor; PYRIN-containing APAF1-like Protein 5; NALP6

产品描述:

The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor (NLR) family are critical components of the inflammasome that link danger-signals to caspase-1 activation. NLRP6/NALP6 is important for intestinal homeostasis by sensing pathogenic commensal bacteria and activating bactericidal activity of macrophages through secretion of IL-18. NLRP6 suppresses inflammation and carcinogenesis by regulating tissue repair and deletion of NLRP6 gene accelerated colitis-associated tumor growth in mice.

宿主来源:

Purified from concentrated hybridoma tissue culture supernatant.

实验应用:

IHC, WB

靶标/特异性:

Recognizes human NLRP6.

同种型:

Mouse IgG1kappa

免疫原:

Recombinant human NLRP6 (NACHT domain).

克隆号:

Clint-1