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折扣/货期| 货号：AG-25A-0105-C100 | 规格：100 ug | 目录价：￥1920 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-NQO1 (human), pAb
别名:
NAD(P)H Dehydrogenase (Quinine) 1 (NQO1); Quinone Reductase 1 (QR1); DT-Diaphorase (DTD); Azoreductase; Phylloquinone Reductase; Menadione Reductase; Dioxin-inducible 1; Disphorase-4 (DIA4); NAD(P)H:Quinone Oxireductase; NAD(P)H:Quinone Oxidoreductase 1
产品描述:
NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body’s protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer’s disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.
宿主来源:
Rabbit
实验应用:
ELISA, WB
靶标/特异性:
Recognizes human NQO1. Detects a band of ~30kDa by Western blot.
免疫原:
Recombinant human NQO1.
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
产地:
瑞士
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