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折扣/货期| 货号：AG-20B-0002-C100 | 规格：100 ug | 目录价：￥3960 |
| 货号：AG-20B-0002-TRIAL | 规格：25 ug | 目录价：￥1740 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-NS5B (HCV), mAb (5B-3B1) (25 ug)
别名:
Nonstructural Protein 5B
产品描述:
The NS3 serine protease, in association with NS4A, is responsible for the cleavages of the Hepatitis C virus protease complexes NS3-NS4A, NS4A-NS4B, NS4B-NS5A and NS5A-NS5B. NS5B is a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Hepatitis C virus protease NS3-NS4A colocalizes with IPS-1/VISA/MAVS/Cardif in the mitochondrial membrane and has been shown to cleave the TLR3 adapter TRIF and Cardif to eliminate the antiviral signaling pathways. NS3-NS4A represents an important target for anti-HCV drugs.
宿主来源:
Purified from concentrated hybridoma tissue culture supernatant.
实验应用:
WB
靶标/特异性:
Recognizes HCV NS5B (epitope mapped to NS5B aa 372-382). It recognizes genotype 1 a and also 1b (albeit with lower affinity). It does not recognize genotype 2a.
同种型:
Mouse IgG2b
免疫原:
Recombinant hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase (genotype 1a).
克隆号:
5B-3B1
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
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