anti-NS5B (HCV), mAb (blocking) (5B-12B7) (25 ug)-单抗-深圳欣博盛生物科技有限公司

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anti-NS5B (HCV), mAb (blocking) (5B-12B7) (25 ug)

品牌：Adipogen

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说明书

折扣/货期

货号：AG-20B-0003-C100	规格：100 ug	目录价：￥3960
货号：AG-20B-0003-TRIAL	规格：25 ug	目录价：￥1740

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-NS5B (HCV), mAb (blocking) (5B-12B7) (25 ug)

别名:

Nonstructural Protein 5B

产品描述:

The NS3 serine protease, in association with NS4A, is responsible for the cleavages of the Hepatitis C virus protease complexes NS3-NS4A, NS4A-NS4B, NS4B-NS5A and NS5A-NS5B. NS5B is a RNA-dependent RNA polymerase that plays an essential role in the virus replication. Hepatitis C virus protease NS3-NS4A colocalizes with IPS-1/VISA/MAVS/Cardif in the mitochondrial membrane and has been shown to cleave the TLR3 adapter TRIF and Cardif to eliminate the antiviral signaling pathways. NS3-NS4A represents an important target for anti-HCV drugs.

宿主来源:

Purified from concentrated hybridoma tissue culture supernatant.

实验应用:

FUNC (Blocking), ICC, IP

靶标/特异性:

Recognizes HCV NS5B from HCV genotype 1 (epitope mapped to NS5B aa 139-392). Does not react with genotype 2.

同种型:

Mouse IgG2a

免疫原:

Recombinant hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase.

克隆号:

5B-12B7