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折扣/货期| 货号：AG-25T-0002-R100 | 规格：100 ul | 目录价：￥2640 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-PARP-1 [ARTD1] (human), pAb
别名:
Poly(ADP-ribose) Polymerase 1; ADP-ribosyltransferase Diphtheria Toxin-like 1; NAD(+) ADP-ribosyltransferase 1
产品描述:
PARP-1 (ARTD1) is involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARP-1 positively regulates the transcription of MTUS1 and negatively regulates the transcription of MTUS2/TIP150. It forms a complex with EEF1A1 and TXK that acts as a T-helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
宿主来源:
Rabbit
实验应用:
ICC, IHC, IP, WB
靶标/特异性:
Recognizes human PARP-1. Cross-reacts weakly with mouse and monkey PARP-1.
免疫原:
Recombinant human PARP-1 [ARTD1] (aa 215-525).
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. Contains 0.1% sodium azide.
产地:
瑞士
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