官网链接
折扣/货期| 货号：V2601SAF-100UG | 规格：100 ug | 目录价：￥6652.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Anti-Perlecan Antibody (HSPG)
产品描述:
This mAb specifically precipitates heterogeneous material of high MW, identified as perlecan, a major heparan-sulfate proteoglycan (HSPG) within all basement membranes and cell surfaces. It does not cross-react with laminin, fibronectin, or dermatran sulfate proteoglycan. Because of perlecan s strategic location and ability to store and protect growth factors, it has been strongly implicated in the control of tumor cell growth and metastatic behavior. Perlecan possesses angiogenic and growth-promoting attributes primarily by acting as a co-receptor for basic fibroblast growth factor (FGF-2). Suppression of perlecan causes substantial inhibition of neoplastic growth and neovascularization. Thus, perlecan is a potent inducer of neoplasm growth and angiogenesis in vivo and therapeutic interventions targeting this key modulator of tumor progression may improve neoplastic treatment.
反应种属:
Human
宿主来源:
Rat
实验应用:
IHC-P
同种型:
Rat IgG2a, kappa
免疫原:
A murine EHS laminin preparation was used as the immunogen for the anti-Perlecan antibody.
克隆性:
Monoclonal (rat origin)
克隆号:
SPM255
纯化方式:
Protein G affinity chromatography
保存温度:
Store the anti-Perlecan antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
产品形式:
Purified
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
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