官网链接
折扣/货期| 货号：V9744-100UG | 规格：100 ug | 目录价：￥6652.1 |
| 货号：V9744-20UG | 规格：20 ug | 目录价：￥3082.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
HDAC3 Antibody
产品描述:
In the intact cell, DNA closely associates with histones and other nuclear proteins to form chromatin. The remodeling of chromatin is believed to be a critical component of transcriptional regulation and a major source of this remodeling is brought about by the acetylation of nucleosomal histones. Acetylation of lysine residues in the amino-terminal tail domain of histone results in an allosteric change in the nucleosomal conformation and an increased accessibility to transcription factors by DNA. Conversely, the deacetylation of histones is associated with transcriptional silencing. Several mammalian proteins have been identified as nuclear histone acetylases, including GCN5, PCAF (p300/CBP-associated factor), p300/CBP and the TFIID subunit TAF II p250. Mammalian HDAC1 (also designated HD1), HDAC2 (also designated RPD3) and HDAC3, all of which are related to the yeast transcriptional factor Rpd3p, have been identified as histone deacetylases.
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, WB, FACS, IF
同种型:
Mouse IgG2b
免疫原:
Recombinant full-length human HDAC3 protein was used as the immunogen for the HDAC3 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
PCRP-HDAC3-3C9
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the HDAC3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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