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折扣/货期| 货号：AG-25A-0093-C100 | 规格：100 ug | 目录价：￥3000 |
| 货号：AG-25A-0093-TRIAL | 规格：25 ug | 目录价：￥1620 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-Progranulin (mouse), pAb (25 ug)
别名:
Proepithelin; PEPI; PC Cell-derived Growth Factor
产品描述:
Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer‘s Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis.
宿主来源:
Rat
实验应用:
ELISA, WB
靶标/特异性:
Recognizes mouse progranulin. Detects a band of ~90kDa by Western blot. Weakly cross-reacts with human progranulin.
免疫原:
Recombinant mouse progranulin.
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
产地:
瑞士
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