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折扣/货期| 货号：AG-25T-0120-C100 | 规格：100 ug | 目录价：￥6120 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-Slc7a8 [Lat2], pAb
别名:
Solute Carrier Family 7 Member 8; Lat2; L-type Amino Acid Transporter 2; Large Neutral Amino Acids Transporter Small Subunit 2
产品描述:
L-type amino acid transporter (LAT) family members are Na(+)-independent transporters, which deliver neutral amino acids into cells. The four LATs, LAT1 (SLC7A5), LAT2 (SLC7A8), LAT3 (SLC43A1) and LAT4 (SLC43A2) are responsible for the majority of cellular leucine uptake. They show increased expression in many cancers and are critical for control of protein translation and cell growth through the mTORC1 pathway. The increased transporter expression observed in cancers is regulated by transcriptional pathways such as hormone receptors, c-myc and nutrient starvation responses.
宿主来源:
Rabbit
实验应用:
IHC, WB
靶标/特异性:
Recognizes mouse and rat Slc7a8. Detects a ~50kDa Slc7a8 band in wild type mouse brain, kidney, jejunum, ileum and other tissues, which is absent in knock-out animals. In some tissues the antibody detects an additional unknown 38kDa band.
免疫原:
Synthetic peptide corresponding to a partial sequence of mouse Slc7a8 (Q9QXW9).
产品浓度:
0.5mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 1mg/ml BSA and 0.02% sodium azide.
产地:
瑞士
纯度:
Antigen affinity purified.
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