官网链接
折扣/货期| 货号：AG-25A-0058-C100 | 规格：100 ug | 目录价：￥3000 |
| 货号：AG-25A-0058-TRIAL | 规格：25 ug | 目录价：￥1620 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-ST2 (human), pAb (25 ug)
别名:
Interleukin-1 Receptor-like 1; IL-1 Receptor-like 1; IL1RL1; Interleukin-33 Receptor; IL-33-Receptor
产品描述:
ST2 is a member of the Toll/IL-1 receptor family. Two forms of the protein exist, a soluble form known as ST2 and a membrane anchored form known as ST2L. The membrane form is expressed by Th2 cells and bone marrow derived mast cells, whereas the soluble form is expressed by serum-stimulated fibroblasts. It binds IL-33 and is structurally similar to IL-1R1. Type 2 innate lymphoid cells (ILC2), originally referred to as natural helper (NH) cells, are a novel target of IL-33. Lung ILC2s participate in the induction of airway inflammation in influenza virus-infected mice and papain-administrated mice. Soluble ST2 plays a role in protecting ILC2 from IL-33 stimulation and thereby maintaining them in a naïve state and might be important for the regulation of several disease. Blocking with anti-ST2 antibodies has been shown to alleviate experimental arthritis and airway inflammation. The IL-33-ST2 axis is is involved across a range of diseases including asthma, allergies, obesity and cardiac disease.
宿主来源:
Rabbit
实验应用:
ELISA, FACS, WB
靶标/特异性:
Recognizes soluble human ST2. Detects a band of ~50kDa by Western blot and the endogenous ST2 by Flow Cytometry.
免疫原:
Recombinant human soluble ST2.
产品浓度:
1mg/ml
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. In PBS containing 0.02% sodium azide.
产地:
瑞士
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