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折扣/货期| 货号：REV-31-1365-00-R100 | 规格：100 ul | 目录价：￥5726 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-Stat6, Rabbit Monoclonal (RM473)
别名:
Signal Transducer and Activator of Transcription 6
产品描述:
STAT6 (Signal transducer and activator of transcription 6) is a transcription factor that belongs to the Signal Transducer and Activator of Transcription (STAT) family of proteins. The proteins of STAT family transmit signals from a receptor complex to the nucleus and activate gene expression. STAT6 is activated by the binding of interleukin-4 (IL-4) to its receptor. IL-4 is a cytokine that is produced by T cells, B cells, and mast cells. When IL-4 binds to its receptor, it triggers a series of events that lead to the phosphorylation of STAT6. Phosphorylated STAT6 then dimerizes and translocates to the nucleus, where it binds to DNA and activates the transcription of a number of genes. The genes that are activated by STAT6 play a role in a number of different biological processes, including Th2 cell differentiation, IgE production, eosinophil differentiation, mast cell activation and is involved in the development of some types of cancer.
宿主来源:
Rabbit
实验应用:
IHC, WB
靶标/特异性:
RM473 reacts to human Stat6.
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to residues near the C-terminus of human Stat6.
克隆号:
RM473
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
上一个:anti-FAK (Focal adhesion kinase 1), Rabbit Monoclonal (RM472)
下一个:anti-5-Formylcytosines (5-fC), Rabbit Monoclonal (RM477)
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