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折扣/货期| 货号：REV-31-1399-00-R100 | 规格：100 ul | 目录价：￥5726 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
anti-UP2 (Uroplakin-2) (human), Rabbit Monoclonal (RM507)
别名:
Uroplakin-2; UPII; Uroplakin II
产品描述:
The protein components of uroplaques are composed of uroplakins (UPs), which are a family of transmembrane proteins, including UPIa (27 kDa), UPIb (28 kDa), UPII (15 kDa), and UPIIIa (47 kDa). UPs are exclusively expressed in the normal urothelium and are undetectable in non-urothelial tissues. They are usually present at the apical surface and cytoplasm of umbrella cells but absent in the intermediate and basal cells. Although UPs are the major differentiation products of the urothelium, they are not significantly downregulated during urothelial malignant transformation. Using immunohistochemical staining it was shown that more than half of invasive and metastatic urothelial carcinomas (UCs) continued to express UPs. Uroplakin II (UP II) is a 15 kDa protein component of urothelial plaques that enhance the permeability barrier of the urothelium. Uroplakin II (UPII) is considered as a sensitive marker for urothelial carcinoma (UC).
宿主来源:
Rabbit
实验应用:
IHC, WB
靶标/特异性:
This antibody reacts to human UP2.
同种型:
Rabbit IgG
免疫原:
A peptide corresponding to residues near the C-terminus of human UP2.
克隆号:
RM507
产品浓度:
N/A
保存温度:
+4°C
运输温度:
BI
产品形式:
liquid
存储溶液:
Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide.
产地:
瑞士
纯度:
Protein A purified.
上一个:anti-DNA-PKcs (human), Rabbit Monoclonal (RM505)
下一个:anti-Phosphotyrosine, Rabbit Monoclonal (RM111)
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