anti-VISTA, Rabbit Monoclonal (RM503)-单抗-深圳欣博盛生物科技有限公司

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anti-VISTA, Rabbit Monoclonal (RM503)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：REV-31-1395-00-R100

规格：100 ul

目录价：￥5726

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

anti-VISTA, Rabbit Monoclonal (RM503)

别名:

B7-H5; V-type Immunoglobulin Domain-containing Suppressor of T Cell Activation; Platelet Receptor Gi24; Stress-induced Secreted Protein-1; Sisp-1; V-set Domain-containing Immunoregulatory Receptor

产品描述:

Human VISTA is a 55 to 65kDa type I Ig membrane protein with the extracellular domain homologous to PD-L1. VISTA is mainly expressed on hematopoietic tissues (spleen, thymus and bone marrow) and on myeloid cells with lower expression on CD4+ and CD8+ T cells. VISTA is a new negative checkpoint regulator that potently suppresses T cell activation. Overexpression of VISTA on tumors inhibits the protective anti-tumor immunity and blockade of VISTA enhances antitumor immunity in multiple tumor models. VISTA on APC delivers negative signaling to T cells via a yet-to-identify binding partner on T cells.

宿主来源:

Rabbit

实验应用:

IHC, WB

靶标/特异性:

This antibody reacts to human, mouse or rat VISTA.

同种型:

Rabbit IgG

免疫原:

A peptide corresponding to residues near the C-terminus of human VISTA.

克隆号:

RM503