官网链接
折扣/货期| 货号：RQ7647 | 规格：100 ug | 目录价：￥6488.05 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
ANXA1 Antibody / Annexin A1
产品描述:
ANXA1, also known as lipocortin I or Annexin A1, is a protein that in humans is encoded by the ANXA1 gene. It is mapped to 9q21.13. ANXA1 belongs to a family of Ca(2+)-dependent phospholipid binding proteins which have a molecular weight of approximately 35,000 to 40,000 and are preferentially located on the cytosolic face of the plasma membrane. ANXA1 protein has an apparent relative molecular mass of 40 kDa, with phospholipase A2 inhibitory activity. Lower peptide concentrations possibly found in inflammatory situations elicit Ca(2+) transients without fully activating the mitogen-activated protein kinase pathway. This causes a specific inhibition of the transendothelial migration of neutrophils and a desensitization of neutrophils toward a chemoattractant challenge. These findings identified ANXA1 peptides as novel, endogenous FPR ligands and established a mechanistic basis of ANXA1-mediated antiinflammatory effects.
反应种属:
Human
宿主来源:
Mouse
实验应用:
WB, IHC-P, FACS
同种型:
Mouse IgG2b
免疫原:
E. coli-derived recombinant human protein (amino acids A2-N346) was used as the immunogen for the ANXA1 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
6B7F8
纯化方式:
Antigen affinity purified
保存温度:
After reconstitution, the ANXA1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
产品形式:
Antigen affinity purified
存储溶液:
0.5mg/ml if reconstituted with 0.2ml sterile DI water
产地:
美国
您可能感兴趣的产品
H2AX Phospho-Ser 139 (1H2) Monoclonal Antibody
货号：G01106.100 µL
TLF (TBP like factor) Monoclonal Antibody
货号：G01105.100 µL
TIF2 Monoclonal Antibody
货号：G01104.100 µL
TIF2 Monoclonal Antibody
货号：G01103.100 µL
TIF1δ(Transcriptional intermediary factor 1d) Monoclonal Antibody
货号：G01102.100 µL
TIF1 γ Monoclonal Antibody
货号：G01101.100 µL
TIF1 β Monoclonal Antibody
货号：G01100.100 µL
TIF1 α Monoclonal Antibody
货号：G01099.100 µL
促销活动
复制QQ号成功，请打开QQ后添加好友进行咨询