APAF1 antibody [C3], C-term-多抗-深圳欣博盛生物科技有限公司

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APAF1 antibody [C3], C-term

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX101067	规格：100μl	目录价：￥4000
货号：GTX101067-S	规格：25μl	目录价：￥1700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

APAF1 antibody [C3], C-term

别名:

apoptotic peptidase activating factor 1 , APAF-1 , CED4

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

IHC-P

同种型:

IgG

免疫原:

Recombinant protein encompassing a sequence within the C-terminus region of human APAF1. The exact sequence is proprietary.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

0.51 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 1% BSA, 20% Glycerol, 0.01% Thimerosal.

生产商:

GeneTex

功能与背景:

This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq]

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