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折扣/货期| 货号：SIH-346-5MG | 规格：5 mg | 目录价：￥4060.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Apicidin
别名:
(3S,6S,9S,15aR)-9-[(2S)-2-Butanyl]-6-[(1-methoxy-1H-indol-3-yl)methyl]-3-(6-oxooctyl)octahydro-2H-pyrido[1,2-a][1,4,7,10]tetraazacyclododecine-1,4,7,10(3H,12H)-tetrone; Cyclo(N-O-methyl-L-tryptophanyl-L Lisoleucinyl-Dpipecolinyl-L-2-amino-8-oxodecanoyl)
产品描述:
HDAC inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
623.8
产品形式:
White Solid
产地:
加拿大
功能与背景:
Cyclopeptide inhibitor of histone deactylases (HDACs). Inhibits HeLa cell proliferation (IC50=50-100 nM) and induces reversible transcriptional activation of p21 (WAF1). Decreases HIF1α protein levels and transcriptional activity in human and mouse tumor cell lines. Cell permeable.
纯度:
>98% (HPLC); NMR (conforms)
来源:
Synthetic
CAS号:
183506-66-3
分子式:
C34H49N5O6
溶解度:
Soluble in 10 mg/ml DMSO or 100% Ethanol
PubChem CID:
6918328
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