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折扣/货期| 货号：60-931 | 规格：400 ul | 目录价：￥8687.25 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
APOBEC3A Antibody
别名:
DNA dC->dU-editing enzyme APOBEC-3A, A3A, 354-, Phorbolin-1, APOBEC3A
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit Ig
克隆性:
Polyclonal
纯化方式:
This antibody is purified through a protein A column, followed by peptide affinity purification.
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Supplied in PBS with 0.09% (W/V) sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
This gene is a member of the cytidine deaminase gene
family. It is one of seven related genes or pseudogenes found in a
cluster, thought to result from gene duplication, on chromosome 22.
Members of the cluster encode proteins that are structurally and
functionally related to the C to U RNA-editing cytidine deaminase
APOBEC1. The protein encoded by this gene lacks the zinc binding
activity of other family members. The protein plays a role in
immunity, by restricting transmission of foreign DNA such as
viruses. One mechanism of foreign DNA restriction is deamination of
foreign double-stranded DNA cytidines to uridines, which leads to
DNA degradation. However, other mechanisms are also thought to be
involved, as anti-viral effect is not dependent on deaminase
activity. One allele of this gene results from the deletion of
approximately 29.5 kb of sequence between this gene, APOBEC3A, and
the adjacent gene APOBEC3B. The breakpoints of the deletion are
within the two genes, so the deletion allele is predicted to have
the promoter and coding region of APOBEC3A, but the 3' UTR of
APOBEC3B.
Accession #:
P31941
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