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折扣/货期| 货号：60-930 | 规格：400 ul | 目录价：￥8687.25 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
FBXW4 Antibody
别名:
F-box/WD repeat-containing protein 4, Dactylin, F-box and WD-40 domain-containing protein 4, FBXW4, FBW4, SHFM3
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit Ig
克隆性:
Polyclonal
纯化方式:
This antibody is purified through a protein A column, followed by peptide affinity purification.
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
Supplied in PBS with 0.09% (W/V) sodium azide.
产地:
美国
生产商:
Prosci
功能与背景:
This gene is a member of the F-box/WD-40 gene family,
which recruit specific target proteins through their WD-40
protein-protein binding domains for ubiquitin mediated degradation.
In mouse, a highly similar protein is thought to be responsible for
maintaining the apical ectodermal ridge of developing limb buds;
disruption of the mouse gene results in the absence of central
digits, underdeveloped or absent metacarpal/metatarsal bones and
syndactyly. This phenotype is remarkably similar to split
hand-split foot malformation in humans, a clinically heterogeneous
condition with a variety of modes of transmission. An autosomal
recessive form has been mapped to the chromosomal region where this
gene is located, and complex rearrangements involving duplications
of this gene and others have been associated with the condition. A
pseudogene of this locus has been mapped to one of the introns of
the BCR gene on chromosome 22.
Accession #:
P57775
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