深圳欣博盛生物科技有限公司 a1

ARB-272572
货号:42547-1 mg 规格:1 mg 目录价:¥375
货号:42547-10 mg 规格:10 mg 目录价:¥2948
货号:42547-25 mg 规格:25 mg 目录价:¥5534
货号:42547-5 mg 规格:5 mg 目录价:¥1675
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ARB-272572
产品描述:
A PD-1/PD-L1 interaction inhibitor (IC50 = 400 pM in an HTRF assay); inhibits the PD-1/PD-L1 interaction in a cell-based NFAT reporter assay (IC50 = 17 nM); decreases cell surface levels of PD-L1 in primary human dendritic cells and B cells; reduces CMV antigen-induced IFN-γ production in a CMV recall assay using PBMCs isolated from CMV seropositive patients (IC50 = 3 nM); induces T cell proliferation and IFN-γ production in PBMCs isolated from patients with chronic HBV infection at 500 nM in the presence of HBV peptides; reduces tumor volume and PD-L1 levels in CD45- tumor cells in a humanized MC-38 murine model of colon cancer at 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
568.66628
产品形式:
A solid
纯度:
≥98%
CAS号:
2368182-63-0
分子式:
C32H36N6O4
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