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折扣/货期| 货号：30695-1 mg | 规格：1 mg | 目录价：￥925 |
| 货号：30695-10 mg | 规格：10 mg | 目录价：￥4409 |
| 货号：30695-5 mg | 规格：5 mg | 目录价：￥2452 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Arenobufagin
产品描述:
A cardiotonic steroid with anticancer activity; inhibits Na+/K+-ATPase activity in isolated guinea pig ventricular myocytes (IC50 = 290 nM); increases cleavage of PARP, caspase-3, and caspase-9, as well as induces apoptosis in HepG2 hepatocellular carcinoma cells; It inhibits proliferation of HepG2, Hep3B, BEL-7402, and MCF-7 cancer cells (IC50s = 101.9, 39.8, 416.3, and 143.7 nM, respectively), as well as multidrug-resistant HepG2/adm and MCF-7/adr cancer cells (IC50s = 730 and 67.5 nM, respectively); reduces tumor growth, the number and size of lung metastases, and tumor levels of the EMT markers vimentin and β-catenin in a PC3 mouse xenograft model at 1 mg/kg; inhibits VEGF-induced angiogenesis in a Matrigel™ plug assay in mice at 5 and 10 µM/plug
保存温度:
-20
运输温度:
-20
预期分子量:
416.50728
产品形式:
A crystalline solid
纯度:
≥95%
来源:
Plant/Bufonis Venenum
CAS号:
464-74-4
分子式:
C24H32O6
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