| 货号:30686-10 mg | 规格:10 mg | 目录价:¥3069 |
| 货号:30686-25 mg | 规格:25 mg | 目录价:¥5601 |
| 货号:30686-5 mg | 规格:5 mg | 目录价:¥1621 |
| 货号:30686-50 mg | 规格:50 mg | 目录价:¥8777 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
SD-06
别名:
SD-006
产品描述:
An inhibitor of p38α MAPK (IC50 = 0.016 µM); selective for p38α over p38β, p38γ, and p38δ MAPKs (IC50s = 0.677, >100, and >100 µM, respectively), as well as a panel of 54 additional kinases (IC50s = >3 µM for all); inhibits LPS-induced TNF-α, IL-6, and IL-1β release from primary human monocytes (IC50s = 79.4, 106.9, and 105.9 nM, respectively); decreases IL-1β-induced production of PGE2 in patient-derived RASFs (IC50 = 96.2 nM); reduces carrageenan-induced paw swelling and hyperalgesia in rats at 30 mg/kg; reduces the incidence of arthritis in a mouse model of collagen-induced arthritis; protects against joint and bone destruction in a rat model of streptococcal cell wall-induced arthritis
保存温度:
-20
运输温度:
-20
预期分子量:
397.858
产品形式:
A solid
纯度:
≥98%
CAS号:
271576-80-8
分子式:
C20H20ClN5O2
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