登革热病毒抗体推荐
The Dengue virus (DEN) is of the genus Flavivirus and possesses a positive-strand RNA genome of approximately 10.6 kb that contains a single open-reading frame encoding for a polyprotein， which can be further cleaved by cellular and viral proteases into three structural proteins (capsid protein C, membrane protein M, envelope protein E), and seven non-structural proteins (NS 1, NS2a, NS2b, NS3, NS4a, NS4b, NS5). There are four serotypes (DEN 1-4), though there is certainly genotypic variability in individual viral genomes within each serotype. This variability is thought to have minimal clinical significance , as human infection from any of the four serotypes results in long-term immunity to that serotype . However, cross-immunity between serotypes is of much shorter duration , meaning that many people are victims of sequential infection by different serotypes. This is clinically very important, as sequential infection appears to be a risk factor for more serious disease manifestations.
登革热病毒抗体推荐
Dengue Virus Protein Schematic Diagram (Non-Structural Proteins (Orange)
Dengue virus 1, 2, 3 & 4 antibody [D1-11 (3)] (GTX29202) NS1 (Dengue virus ) antibody [GT1 061] (GTX630SS7)
Dengue virus antibody detects Dengue virus 1 protein at NS1 antibody detects NS1 (Dengue virus) protein at
cytoplasm by immunofluorescent analysis cytoplasm by immunofluorescent analysis
Envelope protein (Dengue virus) antibody [GT214] (GTX629116) WB analysis for all blots
Envelope protein antibody detects Envelope protein (Dengue A: BHK-21; B: DEN2-infecled BHK-21; C: JEV-infecled BHK
virus) protein at cytoplasm by immunofluorescent analysis -21 Blols probed wilh Rb pAb 10 (Ieft 10 righl): NS1 (GTX124
280); NS2B (GTX124246); NS3 (GTX124252); NS4B (GTX124
250); NS5 (GTX124253)
Cat.NO | Product | Reactivity | Host&Clonality | Application |
GTX29202 | Dengue Virus 1, 2, 3 & 4 antibody [D1-11(3)] | DEN | Ms mAb IgG2a | Dot blot, ELlSA, ICC/IF, WB |
GTX41428 | Dengue Virus Type 2 antibody [NYRDeng2] | DEN2 | Ms mAb IgG1 | ELISA. WB |
GTX43295 | Dengue Types 1,2,3,4 antibody [BDI419] | DEN | Ms mAb IgG2a | Dot blot, ELlSA, ICC川F |
GTX41437 | Dengue Virus antibody [5161] | DEN | Ms mAb IgG2a | ELISA |
GTX41430 | Dengue Virus Type 2 antibody [3H5.1] | DEN2 | Ms mAb IgG1 | ICC/IF |
GTX43296 | Dengue Type 2, envelope antibody [B932M] | DEN2 | Ms mAb IgG1 | ICC/IF |
GTX124247 | Capsid Protein (Dengue Virus) antibody | Capsid (DEN) | Rb pAb | WB |
GTX103343 | Capsid Protein (Dengue Virus) antibody | Capsid (DEN) | Rb pAb | ICC/IF. WB |
GTX128092 | PrM (Dengue Virus) antibody | PrM (DEN) | Rb pAb | WB |
GTX128093 | PrM (Dengue Virus) antibody | PrM (DEN) | Rb pAb | WB |
GTX127277 | Envelope protein (Dengue Virus) antibody | Envelope (DEN) | Rb pAb | ICC/IF. WB |
GTX629116 | Envelope protein (Dengue Virus) antibody [GT214] | Envelope (DEN) | Ms mAb IgG2a | ICC/IF. WB |
GTX629117 | Envelope protein (Dengue Virus) antibody [GT643] | Envelope (DEN) | Ms mAb IgG2b | ICC/IF. WB |
GTX630557 | NS1 (Dengue virus) antibody [GT1061] | NS1 (DEN) | Ms mAb IgG1(NEW Producr) | ICC/IF. WB |
GTX630556 | NS1 (Dengue virus) antibody [GT4212] | NS1 (DEN) | Ms mAb IgG2a(NEW Producr) | ICC/IF. WB |
GTX103346 | NS1 (Dengue Virus 2) antibody | NS1 (DEN2) | Rb pAb | ICC/IF. WB |
GTX124280 | NS1 (Dengue Virus) antibody | NS1 (DEN) | Rb pAb | ICC/IF. WB |
GTX124246 | NS2B (Dengue Virus) antibody | NS2B (DEN) | Rb pAb | ICC/IF. WB |
GTX124252 | NS3 (Dengue Virus) antibody | NS3 (DEN) | Rb pAb | ICC/IF. WB |
GTX629477 | NS3 (Dengue Virus) antibody [GT2811] | NS3 (DEN) | Ms mAb IgG1 | ICC/IF. WB |
GTX124249 | NS4A (Dengue Virus) antibody | NS4A (DEN) | Rb pAb | WB |
GTX103349 | NS4B (Dengue Virus) antibody | NS4B (DEN) | Rb pAb | ICC/IF. WB |
GTX124250 | NS4B (Dengue Virus) antibody | NS4B (DEN) | Rb pAb | ICC/IF. WB |
GTX103350 | NS5 (Dengue Virus) antibody | NS5 (DEN) | Rb pAb | ICC/IF. WB |
GTX124253 | NS5 (Dengue Virus) antibody | NS5 (DEN) | Rb pAb | ICC/IF. WB |
GTX629446 | NS5 (Dengue Virus 2) antibody [GT353] | NS5 (DEN) | Ms mAb IgG2b | ICC/IF. WB |
GTX629447 | NS5 (Dengue Virus 2) antibody [GT361] | NS5 (DEN) | Ms mAb IgG1 | ICC/IF. WB |
Dengue infections are caused by four closely related viruses named DEN-1, DEN-2, DEN-3, and DEN-4. These four viruses are called
serotypes. All four dengue serotypes circulate together in tropical and subtropical regions around the world.
The Viral genome is translated as a single, long polypeptide and then cut into ten proteins.
Three are structural proteins: the capsid (C), envelope (E), and membrane (M) proteins. Seven are nonstructural proteins: NS1, NS2A,
NS2B, NS3, NS4A, NS4B, and NS5. These nonstructural proteins play roles in viral replication and assembly.
Proteins | Functions | GeneTex Antibodies | |
Structure | Capsid | Encapsidation of the RNA genome. May regulate host | GTX124247, GTX103343 |
Envelope | Allowing virus to enter host cells. Essential target of | GTX43296 | |
Membrane | Compose viral membrane structure | GTX127277, GTX629116, | |
Non-Structure | NS1 | Essential for virus replication, as a target of humural | GTX630556, |
NS2A, 2B | Viral RNA synthesis, virion assembly/maturation, and | GTX124246 (2B) | |
NS3 | Protease/ nucleotide triphosphatases and helicase | GTX124252, GTX629477, | |
NS4A, 4B | Blocking IFNa/b signaling and involved in STAT pathway | GTX124249 (4A), GTX103349 (4B), | |
NS5 | Viral RNA polymerase and methyltransferase. | GTX103350, GTX124253, | |
GeneTex Antibodies against whole | GTX29202, GTX41428, GTX43295, GTX41437, GTX41430 | ||
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