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折扣/货期| 货号：29708-1 mg | 规格：1 mg | 目录价：￥844 |
| 货号：29708-10 mg | 规格：10 mg | 目录价：￥6084 |
| 货号：29708-25 mg | 规格：25 mg | 目录价：￥9085 |
| 货号：29708-5 mg | 规格：5 mg | 目录价：￥3873 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
AST-1306 (tosylate)
别名:
Allitinib
产品描述:
An irreversible EGFR, HER2, and HER4 inhibitor (IC50s = 0.5, 3, and 0.8 nM, respectively); selective for EGFR, HER2, and HER4 over a panel of 23 additional kinases (IC50s = >10 µM); inhibits EGFRT790M/L858R (IC50 = 12 nM in a cell-free assay); decreases EGFR, ERK1/2, and Akt phosphorylation in Calu-3, A549, and SKOV3 cancer cells from 0.001-1 µM; inhibits proliferation of various cancer cells (IC50s = 0.23-16 µM); reduces tumor growth in Calu-3, A549, SKOV3, and HO8910 mouse xenograft models at 25, 50, and 100 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
448.876583
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1050500-29-2
分子式:
C24H18ClFN4O2 • C7H8O3S
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