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折扣/货期| 货号：29706-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：29706-10 mg | 规格：10 mg | 目录价：￥2492 |
| 货号：29706-25 mg | 规格：25 mg | 目录价：￥5628 |
| 货号：29706-5 mg | 规格：5 mg | 目录价：￥1715 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Upadacitinib
别名:
ABT-494
产品描述:
A JAK1 inhibitor (IC50 = 47 nM); selective for JAK1 over JAK3 and Tyk2 (IC50s = 2,304 and 4,690 nM, respectively), as well as a panel of 83 additional kinases at 1 µM, but does inhibit JAK2, ROCK1, and ROCK2 (IC50s = 120, 920 and 430 nM, respectively); decreases cytokine-induced STAT phosphorylation in a variety of human cells (IC50s = 1.6-649 nM); reduces M. tuberculosis-induced paw swelling and bone erosion in a rat model of arthritis at 1, 3, and 10 mg/kg twice per day for 17 days
保存温度:
-20
运输温度:
-20
预期分子量:
380.367809
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
1310726-60-3
分子式:
C17H19F3N6O
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