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折扣/货期| 货号：31238-10 mg | 规格：10 mg | 目录价：￥1862.6 |
| 货号：31238-25 mg | 规格：25 mg | 目录价：￥4368.4 |
| 货号：31238-5 mg | 规格：5 mg | 目录价：￥1165.8 |
| 货号：31238-50 mg | 规格：50 mg | 目录价：￥6994.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Atrasentan (hydrochloride)
别名:
A-127722|A-147627|ABT-627
产品描述:
An ETA antagonist (Ki = 69 pM for the human receptor); selective for ETA over ETB (Ki = 139 nM for the human receptor) and a panel of 29 other receptors at 10 µM; inhibits endothelin-1-induced secretion of arachidonic acid from HPSMCs (pA2 = 10.5), as well as endothelin-1-induced vasoconstriction in isolated rat aortic rings (pA2 = 9.2); inhibits endothelin-1-induced increases in the pressor response in normotensive rats at 10 mg/kg; reduces urinary levels of albumin, TGF-β, and a PGE2 metabolite, as well as decreases the number of macrophages, in a rat model of streptozotocin-induced diabetic nephropathy at 5 mg/kg per day
保存温度:
-20
运输温度:
-20
预期分子量:
547.1
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
195733-43-8
分子式:
C29H38N2O6 • HCl
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