深圳欣博盛生物科技有限公司 a1

Azadiradione
货号:37063-1 mg 规格:1 mg 目录价:¥4060.2
货号:37063-5 mg 规格:5 mg 目录价:¥12167.2
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Azadiradione
产品描述:
A limonoid with diverse biological activities; inhibits heparin-induced tau aggregation by 54.2% in a cell-free assay at 400 µM; inhibits the tautomerase activity of human, P. falciparum, and P. yoelii MIF (IC50s = 35.2, 45.6, and 43 µM, respectively); cytotoxic to HL-60 leukemia and SK-BR-3 breast cancer cells (IC50s = 14.7 and 15.9 µM, respectively) but not A549 lung, AZ-521 stomach, or CRL-1579 melanoma cells (IC50s = >20 µM for all); decreases the mutant huntingtin aggregate load in the cortex, striatum, and hippocampus, improves motor function, and increases lifespan in the R6/2 transgenic mouse model of Huntington’s disease at 10 mg/kg; reduces blood glucose levels and α-amylase activity, as well as serum triglyceride and HDL levels, in a rat model of streptozotocin-induced diabetes at 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
450.6
产品形式:
A solid
有效期:
1460
纯度:
≥98%
来源:
Synthetic
CAS号:
26241-51-0
分子式:
C28H34O5
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