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折扣/货期| 货号：37151-100 mg | 规格：100 mg | 目录价：￥4207.6 |
| 货号：37151-25 mg | 规格：25 mg | 目录价：￥1313.2 |
| 货号：37151-250 mg | 规格：250 mg | 目录价：￥9849 |
| 货号：37151-50 mg | 规格：50 mg | 目录价：￥2358.4 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
DUN41875
别名:
SCD1 Inhibitor|Stearoyl-CoA Desaturase 1 Inhibitor|Stearoyl-Coenzyme A Desaturase 1 Inhibitor
产品描述:
A stearoyl-CoA desaturase 1 inhibitor (IC50 = 11.8 nM for the rat enzyme); increases tetramerization of soluble α-synuclein and reduces mutant α-synuclein incorporation into tetramers in BE(2)-M17 cells expressing the 3K mutant α-synuclein at 0.01, 0.1, and 1 µM; reduces the plasma ratio of oleic acid to stearic acid in rats fed a low essential fatty acid diet at 10 or 30 mg/kg; reduces the time to turn and the number of falls in the pole test, increases time to fall from the rotarod, and improves endurance in the hanging wire test in the 3K-3798 transgenic mouse model of Parkinson's disease when administered in the drinking water at 1.9% (v/v); reduces cortex somatic aggregates of phosphorylated α-synuclein and cortex levels of LAMP-1 in the brains from the same mice
保存温度:
-20
运输温度:
-20
预期分子量:
363.337249
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
1295541-87-5
分子式:
C17H16F3N5O
促销活动
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