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折扣/货期| 货号：24934-1 mg | 规格：1 mg | 目录价：￥964.8 |
| 货号：24934-10 mg | 规格：10 mg | 目录价：￥6606.2 |
| 货号：24934-5 mg | 规格：5 mg | 目录价：￥4261.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
AZD 3293
别名:
Lanabecestat|LY3314814
产品描述:
An inhibitor of BACE1 and BACE2 (Kis = 0.4 and 0.8 nM, respectively); selective for BACE1 and BACE2 over cathepsin D, γ-secretase, and hERG (IC50s = 3,797, >25,000, and 4,700 nM, respectively); inhibits the secretion of Aβ40 in primary mouse and guinea pig neuronal cultures (IC50s = 0.61 and 0.31 NM, respectively), as well as in SH-SY5Y cells overexpressing human APP (IC50 = 0.08 nM); reduces plasma and brain levels of Aβ40 and brain levels of Aβ42 in mice at 50, 100, and 200 µmol/kg
保存温度:
-20
运输温度:
-20
预期分子量:
412.52688
产品形式:
A solid
纯度:
≥98%
CAS号:
1383982-64-6
分子式:
C26H28N4O
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