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折扣/货期| 货号：V9714-100UG | 规格：100 ug | 目录价：￥6414.1 |
| 货号：V9714-20UG | 规格：20 ug | 目录价：￥2963.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
B-cell lymphoma/leukemia 11A Antibody / BCL11A
产品描述:
Bcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, FACS, IF
同种型:
Mouse IgG1
免疫原:
Recombinant full-length human protein was used as the immunogen for the B-cell lymphoma/leukemia 11A antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
PCRP-BCL11A-1H3
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the B-cell lymphoma/leukemia 11A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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