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折扣/货期| 货号：AG-40B-0010AF-C010 | 规格：10 ug | 目录价：￥4200 |
| 货号：AG-40B-0010AF-C100 | 规格：100 ug | 目录价：￥20400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
B-Xpander™ CD40L (human) (rec.) (Animal Free)
别名:
MultimericCD40L™ (Animal Free); ACRP30headless:CD40L; ACRP30headless:CD154; ADIPOQ-CD40L; ACRP30headless:TNFSF5
产品描述:
B-Xpander™ is a potent enhanced Multimeric human CD40L cytokine, for B cell activation, B cell expansion (proliferation) and cell therapy applications. In-house production using a proprietary protocol and a characterized and certified CHO cell line allows the supply of the most active Multimeric human CD40L proteins in GMP-like format. Interest in B cells has recently increased in immunotherapies using Engineered B cells or Tumor-Infiltrating Lymphocytes (TILs). However, current methods for B cell expansion are inefficient, time consuming and can lead to insufficient B cell numbers and persistent T cell exhaustion. Our B-Xpander™ protein improves current protocols for B cell stimulation by mimicking the natural interaction between CD40L and CD40 molecules on B cells. B-Xpander™ Quality Features: • Production in characterized and certified CHO cell line (for GMP-grade manufacturing)* • High Bioactivity tested by ELISA/Cell-based Assays • Verified Purity & Homogeneity by SEC • Low Endotoxin Level • Batch-to-Batch Consistency • Animal-component free Production • No cross-linking Reagents necessary
宿主来源:
CHO cells. Produced using animal component-free medium.
靶标/特异性:
Binds to human CD40.
产品浓度:
After reconstitution:for 10µg size: 0.1mg/ml, for 100µg size: 1 mg/ml
保存温度:
+4°C
运输温度:
BI
预期分子量:
~35-40kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS
产地:
瑞士
纯度:
>95% (SDS-PAGE)
生物活性:
Induces B cell activation (as demonstrated by dose-dependent upregulation of CD86) (ED50: <1ng/ml). B cell expansion online protocol available.
内毒素水平:
<0.01EU/µg purified protein (LAL test, Lonza).
上一个:Annexin V (human) (rec.) (ATTO 647N)
下一个:CD40L (human) (multimeric) (rec.) (Certified Serum Grade)
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