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折扣/货期| 货号：GTX04882 | 规格：100μg | 目录价：￥6600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
B3GALNT1 antibody [PA5]
别名:
B3GALNT1,B3GALT3,GLCT3,GLOB,Gb4Cer,P,P1,beta1,3Nacetylgalactosaminyltransferase 1 (globoside blood group),beta3GalT3,galT3,beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
反应种属:
Human
宿主来源:
Mouse
实验应用:
FCM, ICC/IF, TLC
靶标/特异性:
This antibody is specific for Gb4Cer and does not cross react with various glycosphingolipids: LacCer, Gb3Cer, Gg3Cer, Gg4Cer, GM1, GM2, and GM3, determined by ELISA assay. (PMID: 33564002)
同种型:
IgM
免疫原:
Gb4Cer-labeled very long chain fatty acid (VLCFA)
克隆性:
Monoclonal
克隆号:
PA5
纯化方式:
Purified by hydroxyapatite chromatography
偶联:
Unconjugated
产品浓度:
0.5 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). The encoded protein of this gene does not use N-acetylglucosamine as an acceptor sugar at all. [provided by RefSeq, Mar 2017]
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