B7-H4 (human):Fc (mouse) (rec.)-Fc融合蛋白-深圳欣博盛生物科技有限公司

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B7-H4 (human):Fc (mouse) (rec.)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：CHI-HF-211B7H4-C100

规格：100 ug

目录价：￥5390

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

B7-H4 (human):Fc (mouse) (rec.)

别名:

V-set Domain-containing T Cell Activation Inhibitor 1; VTCN1; B7h.5; Immune Costimulatory Protein B7-H4; T Cell Costimulatory Molecule B7x; Protein B7S1

产品描述:

B7-H4 is a B7 family member that negatively regulates T cell immunity by inhibiting of T cell proliferation, cytokine production and cell cycle progression. In vitro, B7-H4 inhibits CD4+ and CD8+ T cell proliferation, cytokine production and generation of alloreactive cytotoxic T cells (CTLs). In vivo, blockade of endogenous B7-H4 by specific monoclonal antibody promotes T cell responses. B7-H4 ia an important negative regulator of innate immunity through growth inhibition of neutrophils. B7-H4 is expressed on some tumor cancer cells. The role of B7-H4 in tumor progression may be to transform precancerous cells and then protect them from immunosurveillance.

宿主来源:

CHO cells

保存温度:

+4°C

运输温度:

预期分子量:

~80kDa (monomer)

产品形式:

solid

存储溶液:

Lyophilized from 0.2µm-filtered solution in PBS.

产地: