BAFF-R (human):Fc (human) (rec.)-Fc融合蛋白-深圳欣博盛生物科技有限公司

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BAFF-R (human):Fc (human) (rec.)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-40B-0027-3050	规格：3 x 50 ug	目录价：￥3840
货号：AG-40B-0027-C050	规格：50 ug	目录价：￥1920

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

BAFF-R (human):Fc (human) (rec.)

别名:

TNFRSF 13C; Tumor Necrosis Factor Receptor Superfamily Member 13C; BR3; BlySR3; CD268; BAFF Receptor

产品描述:

BAFF is mainly produced by innate immune cells such as neutrophils, monocytes, macrophages, dendritic cells, follicular dendritic cells. T cells, activated B cells, some malignant B cells and also non-lymphoid cells like astrocytes, synoviocytes and epithelial cells can also produce BAFF. BAFF binds three distinct receptors (BAFF-R, TACI and BCMA) expressed predominantly on B cells, although activated T cells also express BAFF-R. BAFF is a master regulator of peripheral B cell survival, and together with IL-6, promotes Ig class-switching and plasma cell differentiation . Besides its major role in B cell biology, BAFF co-stimulates activated T cells. Deregulated expression of BAFF leads to autoimmune disorders in mice. In humans, elevated levels of soluble BAFF have been detected in the serum of patients with various autoimmune diseases, such as Sjögren’s syndrome , Rheumatoid Arthritis (RA) , Multiple sclerosis (MS) and Systemic Lupus Erythematosus (SLE) . BAFF is also increased levels in some lymphoid cancers.

宿主来源:

HEK 293 cells

靶标/特异性:

Binds to human and mouse BAFF.

产品浓度:

1mg/ml after reconstitution

保存温度:

+4°C

运输温度:

预期分子量:

~40kDa (SDS-PAGE)

产品形式: