| 货号:V5815-100UG | 规格:100 ug | 目录价:¥6652.1 |
| 货号:V5815-20UG | 规格:20 ug | 目录价:¥3082.1 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BAP1 Antibody / BRCA1-Associated Protein 1
产品描述:
The BAP1 gene belongs to the ubiquitin C-terminal hydrolase subfamily of de-ubiquitination enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germ line mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, Uveal melanoma and cutaneous melanoma.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P
同种型:
Rabbit IgG, kappa
免疫原:
A portion of amino acids 400-729 from human BRCA1-Associated Protein 1 protein was used as the immunogen for the BAP1 antibody.
克隆性:
Recombinant Rabbit Monoclonal
克隆号:
BAP1/9795R
纯化方式:
Protein A affinity
保存温度:
Aliquot the BAP1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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