BCL11A Antibody / B-cell lymphoma/leukemia 11A-单抗-深圳欣博盛生物科技有限公司

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BCL11A Antibody / B-cell lymphoma/leukemia 11A

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V9710SAF-100UG

规格：100 ug

目录价：￥6414.1

产品详情

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产品名称:

BCL11A Antibody / B-cell lymphoma/leukemia 11A

产品描述:

Bcl-11a (CtIP-1, EVI9, B cell chronic lymphocytic leukemia (CLL)/lymphoma 11A) and Bcl-11b (CtIP-2, RIT1, B cell CLL/lymphoma 11B) genes play crucial roles in lymphopoiesis and influence the progression of hematopoietic malignancies. Disruption of the Bcl-11b locus is linked to T cell acute lymphoblastic leukemia, and the loss of heterozygosity in mice results in T cell lymphoma. Bcl-11 proteins are related C2H2 zinc-finger transcription factors that act as transcriptional repressors. Bcl-11b can interact with the metastasis-associated proteins MTA1 and MTA2 through the amino-terminal region. Bcl-11a is essential for postnatal development and normal lymphopoiesis. The Bcl-11a mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with Bcl-6.

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA, WB, FACS, IF

同种型:

Mouse IgG2a

免疫原:

Recombinant full-length human protein was used as the immunogen for the BCL11A antibody.

克隆性:

Monoclonal (mouse origin)