| 货号:GTX31738-PEP | 规格:50μg | 目录价:¥2400 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Bcl2A1 blocking peptide
别名:
Bcl2 Related Protein A1 , Acc-1 , Acc-2 , Acc1 , Acc2 , Bcl2L5 , Bfl1 , Grs , Hbpa1 , Bcl2A1
产品描述:
Bcl2A1 peptide is used for blocking the activity of Bcl2A1 antibody (catalog number GTX31738).
实验应用:
Neutralizing/Inhibition
克隆号:
偶联:
Unconjugated
产品浓度:
200 μg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.
运输温度:
dry ice
产品形式:
Liquid
存储溶液:
PBS, 0.1% BSA, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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