| 货号:V3814-100UG | 规格:100 ug | 目录价:¥6652.1 |
| 货号:V3814-20UG | 规格:20 ug | 目录价:¥3082.1 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BCMA Antibody / CD269 / TNFRSF17
产品描述:
The B cell maturation protein (BCMA) is a type I integral membrane protein that belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is expressed as a 184 amino acid peptide that is expressed only in mature B-lymphocytes and is located on the cis part of the Golgi apparatus. BCMA shares significant homology with TACI (transmembrane activator) within the cysteine-rich domain. TACI has been shown to bind CAML, which induces activation of NFAT (nuclear factor of activated T cells). Both BCMA and TACI have been shown to bind APRIL and TALL-1, which stimulate B cell proliferation in conjunction with other B-cell activators. When overexpressed, TALL-1 stimulates the development of systemic lupus erythaematosus (SLE).
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, IHC-P
同种型:
Mouse IgG2c, kappa
免疫原:
A portion of amino acids 78-184 from the human protein was used as the immunogen for the BCMA antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
BCMA/2366
纯化方式:
Protein G affinity chromatography
保存温度:
Store the BCMA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
产地:
美国
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