BCMA Antibody / CD269 / TNFRSF17-单抗-深圳欣博盛生物科技有限公司

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BCMA Antibody / CD269 / TNFRSF17

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V3814SAF-100UG

规格：100 ug

目录价：￥6652

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

BCMA Antibody / CD269 / TNFRSF17

产品描述:

The B cell maturation protein (BCMA) is a type I integral membrane protein that belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is expressed as a 184 amino acid peptide that is expressed only in mature B-lymphocytes and is located on the cis part of the Golgi apparatus. BCMA shares significant homology with TACI (transmembrane activator) within the cysteine-rich domain. TACI has been shown to bind CAML, which induces activation of NFAT (nuclear factor of activated T cells). Both BCMA and TACI have been shown to bind APRIL and TALL-1, which stimulate B cell proliferation in conjunction with other B-cell activators. When overexpressed, TALL-1 stimulates the development of systemic lupus erythaematosus (SLE).

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA, IHC-P

同种型:

Mouse IgG2c, kappa

免疫原:

A portion of amino acids 78-184 from the human protein was used as the immunogen for the BCMA antibody.

克隆性:

Monoclonal (mouse origin)