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折扣/货期| 货号：44353-1 mg | 规格：1 mg | 目录价：￥630 |
| 货号：44353-10 mg | 规格：10 mg | 目录价：￥5360 |
| 货号：44353-25 mg | 规格：25 mg | 目录价：￥8656 |
| 货号：44353-5 mg | 规格：5 mg | 目录价：￥2988 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BI-907828
别名:
Brigimadlin
产品描述:
An inhibitor of the p53-MDM2 protein-protein interaction (IC50 = 2 nM in a cell-free assay); selective for p53-MDM2 over p53-MDMX (IC50 = 7,944 nM); selectively inhibits the proliferation of Colon-26 cells, which express wild-type p53, over 4T1 and MC-38 cells, which express mutant p53 (IC50s = 259, 5,579, and 9,782 nM, respectively); inhibits the proliferation of SJSA-1 osteosarcoma cells, BJ human foreskin fibroblasts, and hTERT RPE-1 retinal pigment epithelial cells but only induces apoptosis in SJSA-1 cells; induces tumor regression in an SJSA-1 mouse xenograft model and PDX models
保存温度:
-20
运输温度:
-20
预期分子量:
591.464403
产品形式:
A solid
纯度:
≥98%
CAS号:
2095116-40-6
分子式:
C31H25Cl2FN4O3
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