| 货号:29630-1 mg | 规格:1 mg | 目录价:¥509 |
| 货号:29630-10 mg | 规格:10 mg | 目录价:¥4127 |
| 货号:29630-25 mg | 规格:25 mg | 目录价:¥8496 |
| 货号:29630-5 mg | 规格:5 mg | 目录价:¥2211 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BIBX1382
别名:
BIBX 1382 BS
产品描述:
An EGFR inhibitor (IC50 = 3 nM); selective for EGFR over HER2 (IC50 = 3,400 nM), as well as IGF-1R, β-InsRK, c-Met, c-Src, and VEGFR2 (IC50s = >10 µM); inhibits proliferation and colony formation in A549 cancer cells expressing mutant K-Ras, as well as FaDu cancer cells expressing wild-type K-Ras at 5 µM; enhances radiation-induced cytotoxicity in K-Ras-expressing A549 and MDA-MB-231 cancer cells, but not FaDu, HTB-35, or HH4dd cancer cells that express wild-type K-Ras; reduces tumor growth in A431 and FaDu mouse xenograft models at 70 and 60 mg/kg per day, respectively
保存温度:
-20
运输温度:
-20
预期分子量:
387.841743
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
196612-93-8
分子式:
C18H19ClFN7
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