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折扣/货期| 货号：29631-1 mg | 规格：1 mg | 目录价：￥482 |
| 货号：29631-10 mg | 规格：10 mg | 目录价：￥2935 |
| 货号：29631-5 mg | 规格：5 mg | 目录价：￥1608 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CGP 60474
产品描述:
A CDK inhibitor (IC50s = 0.017, 0.08, and 0.05 µM for Cdk1/cyclin B, Cdk2/cyclin A, and Cdk2/cyclin E, respectively); selective for these CDKs over Cdk4/cyclin D1 (IC50 = 0.7 µM) and a variety of other kinases but does inhibit PKCα and v-Abl (IC50s = 0.25 and 0.4 µM, respectively); inhibits proliferation of colon, breast, lung, prostate, and ovarian cancer cells (IC50s = 25-84, 21-280, 40 and 68, 17 and 20, and 18-38 nM, respectively); inhibits poly(I:C)-induced NF-κB nuclear translocation in J774.1 cells at 8 and 32 nM; reduces plasma IL-6 levels and increases survival in a mouse model of LPS-induced endotoxemia at 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
355.82132
产品形式:
A solid
纯度:
≥98%
CAS号:
164658-13-3
分子式:
C18H18ClN5O
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