| 货号:F54131-0.05ML | 规格:0.05 ml | 目录价:¥2962.25 |
| 货号:F54131-0.2ML | 规格:0.2 ml | 目录价:¥6343.55 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BIRC6 Antibody (C-Terminal Region)
产品描述:
Baculoviral IAP repeat-containing protein 6 / APOLLON is an anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification. [UniProt]
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit Ig
免疫原:
A portion of amino acids 4810-4844 from human BIRC6 was used as the immunogen for the BIRC6 antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Antigen affinity
保存温度:
Aliquot the BIRC6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Antigen affinity purified
存储溶液:
In 1X PBS, pH 7.4, with 0.09% sodium azide
产地:
美国
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