| 货号:CHI-HF-220BMP2-C050 | 规格:50 ug | 目录价:¥5740 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BMP-2 (human):Fc (human) (rec.) (non-lytic)
别名:
BMP2; Bone Morphogenetic Protein 2
产品描述:
Bone morphogenetic protein 2 (BMP-2) is a member of the BMP subgroup of the TGF-beta superfamily. It plays a dominant role in embryonic dorsalventral patterning, organogenesis, limb bud formation and bone formation and regeneration. BMP-2 signals through heterodimeric complexes composed of a type I receptor (Activin RI, BMP-RIA or BMP-RIB) and a type II receptor (BMP-RII or Activin RIIB). BMP-2 induces chondrocyte proliferation, endochondral bone formation, longitudinal bone growth and bone and cartilage repair. It induces ectopic bone formation or calcification by promoting osteogenic and chondrogenic differentiation in mesenchymal cells, stem cells and vascular smooth muscle cells. It also promotes the maintenance and repair of colonic epithelium, suppresses neuronal dopamine synthesis and release, induces apoptosis in medulloblastoma cells and is required for cardiac contractility.
宿主来源:
CHO cells
保存温度:
+4°C
运输温度:
BI
预期分子量:
~35-50kDa
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
生物活性:
Shows the biological function of the BMP-2 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain.
内毒素水平:
<1EU/mg protein (LAL test; Lonza).
上一个:CD275 [B7-H2] (human):Fc (human) (rec.) (non-lytic)
下一个:CD200 (human):Fc (human) (rec.) (non-lytic)
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