深圳欣博盛生物科技有限公司 a1

BMPR2 Antibody
品牌:ProSci LLC
货号:19-782 规格:100 uL 目录价:¥7651.8
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
BMPR2 Antibody
别名:
BMPR2, bone morphogenetic protein receptor, type II (serine/threonine kinase), BMPR-II, BMPR3, BMR2, BRK-3, FLJ76945, PPH1, T-ALK, TRG10, bone morphogenetic protein receptor type II, primary pulmonary hypertension 1, serine/threonine kinase, transformatio
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB,IF
同种型:
IgG
克隆性:
Polyclonal
纯化方式:
Affinity purification
偶联:
Unconjugated
产品浓度:
batch dependent
保存温度:
Store at -20˚C. Avoid freeze / thaw cycles.
运输温度:
Blue Ice
产品形式:
Liquid
存储溶液:
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
产地:
美国
生产商:
Prosci
功能与背景:
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.
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