深圳欣博盛生物科技有限公司 a1

BRCA1-Associated Protein 1 Antibody / BAP1
货号:V5816SAF-100UG 规格:100 ug 目录价:¥6652.1
产品详情
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产品名称:
BRCA1-Associated Protein 1 Antibody / BAP1
产品描述:
The BAP1 gene belongs to the ubiquitin C-terminal hydrolase subfamily of de-ubiquitination enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germ line mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, Uveal melanoma and cutaneous melanoma.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P
同种型:
Rabbit IgG, kappa
免疫原:
A portion of amino acids 400-729 from human BAP1 protein was used as the immunogen for the BRCA1-Associated Protein 1 antibody.
克隆性:
Recombinant Rabbit Monoclonal
克隆号:
BAP1/13501R
纯化方式:
Protein A affinity
保存温度:
Aliquot the BRCA1-Associated Protein 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
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