官网链接
折扣/货期| 货号：CDX-B0374-M005 | 规格：5 mg | 目录价：￥1106 |
| 货号：CDX-B0374-M025 | 规格：25 mg | 目录价：￥4424 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Brigatinib
别名:
AP26113; 5-Chloro-N4-[2-(dimethylphosphinyl)phenyl]-N2-[2-methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-2,4-pyrimidinediamine
产品描述:
Brigitanib acts as a tyrosine kinase inhibitor with activity against multiple kinases including ALK, ROS1, insulin-like growth factor 1 receptor and against EGFR deletions and point mutations. It acts by inhibiting ALK phosphorylation and the activation of downstream signaling proteins. It is a highly potent and selective inhibitor of anaplastic lymphoma kinase (ALK). Blocks ALK activity and reduces growth in neuroblastoma cells, mouse xenograft, and Drosophila model systems harboring constitutively active ALK variants. It is potentially useful for the treatment of non-small cell lung cancer (NSCLC). Can be used in combination with anti-EGFR drugs to overcome EGFR mutation resistance.
宿主来源:
Synthetic
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
584.09
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
1197953-54-0
分子式:
C29H39ClN7O2P
您可能感兴趣的产品
O-Carbamyl-D-serine
货号：20324
Benarthin
货号：20323
Ceramidastin, Bacterial ceramidase inhibitor
货号：19378
DDCAD < inhibitor of COMT, cyclic AMP phosphodiesterase and DOPA decarboxylase >
货号：18723
Pyridomycin, Antimycobacterial, Enoyl-ACP Reductase Inhibitor
货号：10080
Probestin, Aminopeptidase M Inhibitor, Aminopeptidase N Inhibitor
货号：367
STAT3-IN-12
货号：44651-10 mg
VRK-IN-1
货号：44649-1 mg
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询