Bupivacaine hydrochloride monohydrate-抑制剂-深圳欣博盛生物科技有限公司

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Bupivacaine hydrochloride monohydrate

品牌：Adipogen

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说明书

折扣/货期

货号：CDX-B0326-G001	规格：1 g	目录价：￥826
货号：CDX-B0326-G005	规格：5 g	目录价：￥1302

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Bupivacaine hydrochloride monohydrate

别名:

1-Butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide; 1-Butyl-2',6'-pipecoloxylidide

产品描述:

Bupivacaine is an amino amide local anesthetic that decreases current amplitude and inhibits whole cell K+ currents in Ca2+-activated K+ channels and N-type voltage-gated (KCNA and KCNC) K+ channels. Bupivacaine also inhibits voltage-gated Na+ channels and tandem pore domain (TASK-2/KCNK-5) K+ channels. The compound is cytotoxic at high concentrations inducing apoptosis and/or necrosis by interference with the mitochondrial energy transduction. Shown to inhibit aerobic ATP synthesis by (i) uncoupling of the oxidative phosphorylation (OXPHOS) and (ii) inhibition of the complex I of the respiratory. Other mechanisms include inhibition of the carnitine-acylcarnitine translocase or activation of the mitochondrial permeability transition pore (MPTP). The analgesic effects of bupivicaine are thought to potentially be due to its binding to the prostaglandin E2 receptors, subtype EP1 (PGE2EP1), which inhibits the production of prostaglandins, thereby reducing fever, inflammation, and hyperalgesia. It is employed as cAMP production inhibitor, it acts as a surfactant molecule possessing both hydrophilic and lipophilic properties, adrenergic antagonist and cholinesterase inhibitor.

宿主来源:

Synthetic

保存温度:

+20°C

运输温度:

Ambient

预期分子量:

288.4. 36.5 . 18.0

产品形式:

solid

产地:

瑞士