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折扣/货期| 货号：SPC-927D-BI | 规格：100 µl | 目录价：￥4888.8 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
BRSK1 Antibody (pThr189): Biotin
别名:
Brain selective kinase 1 Antibody, Brain-specific serine/threonine-protein kinase 1 Antibody, BRSK 1 Antibody, hSAD1 Antibody, SAD1 Antibody, SADB Antibody, Serine/threonine kinase SAD B Antibody
产品描述:
Rabbit Anti-Human BRSK1 (pThr189) Polyclonal
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB | AM
靶标/特异性:
Detects 86.753 kDa.
推荐稀释度:
WB (1:250); optimal dilutions for assays should be determined by the user.
免疫原:
A phospho-specific peptide corresponding to residues surrounding Thr189 of human BRSK1 (AA186-192)
免疫原种属:
Human
克隆性:
Polyclonal
纯化方式:
Peptide Affinity Purified
偶联:
Biotin
保存温度:
Conjugated antibodies should be stored according to the product label
运输温度:
Blue Ice or 4ºC
存储溶液:
PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
产地:
加拿大
功能与背景:
BRSK1 (BR serine/threonine-protein kinase 1), also known as SAD1, is a 794 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one UBA domain and one protein kinase domain. Expressed in a variety of tissues with highest expression in testis and brain, BRSK1 uses magensium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins, including Wee 1 and Cdc25B. Via its kinase activity toward proteins that are involved in microtubule assembly, BRSK1 plays an essential role in neuronal polarization and may be involved in regulating cell cycle arrest in response to DNA damage, Two isoforms of BRSK1 exist due to alternative splicing events.
Accession #:
NP_115806
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