c-Met (phospho Tyr1234) antibody-多抗-深圳欣博盛生物科技有限公司

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c-Met (phospho Tyr1234) antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX02868

规格：100μl

目录价：￥5300

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

c-Met (phospho Tyr1234) antibody

别名:

MET proto-oncogene, receptor tyrosine kinase , AUTS9 , DFNB97 , HGFR , RCCP2 , c-Met

反应种属:

Human, Mouse, Rat

宿主来源:

Rabbit

实验应用:

ELISA, ICC/IF, WB

同种型:

IgG

免疫原:

A synthesized peptide derived from human c-Met around the phosphorylation site of Tyr1234.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

156

产品形式:

Liquid

存储溶液:

PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene encodes a member of the receptor tyrosine kinase family of proteins and the product of the proto-oncogene MET. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that are linked via disulfide bonds to form the mature receptor. Further processing of the beta subunit results in the formation of the M10 peptide, which has been shown to reduce lung fibrosis. Binding of its ligand, hepatocyte growth factor, induces dimerization and activation of the receptor, which plays a role in cellular survival, embryogenesis, and cellular migration and invasion. Mutations in this gene are associated with papillary renal cell carcinoma, hepatocellular carcinoma, and various head and neck cancers. Amplification and overexpression of this gene are also associated with multiple human cancers. [provided by RefSeq, May 2016]

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